Cancer controversy

Screening for prostate cancer: Controversy? What controversy?

for the absence of a reduction in mortality in the plco trial and in comparison with the difference seen in the erspc trial. The truth of the matter is the psa test should not be used at all in screening for prostate cancer in the manner it has heretofore been used. Prostate-specific antigen, discovered in 1970 5,6 , is a normal component of the prostate. It is not cancer-specific. Rather, it i...

Vaccines against cervical cancer provoke US controversy.

Lymphadenectomy for endometrial cancer: the controversy.

Comprehensive surgical staging for endometrial cancer, including hysterectomy, bilateral salpingo-oophorectomy, pelvic washings, and pelvic–aortic lymphadenectomy, defines disease biology and facilitates triage of tailored adjuvant therapy. Recent publication of two randomized trials has cracked the foundation of the house lived in by those believing in the absolute value of endometrial cancer ...

Monitoring ovarian cancer: CA125 trial stirs controversy.

M onitoring ovarian cancer with regular blood tests for the CA125 biomarker is a firmly embedded practice in oncology, the theory being that rising CA125 levels may indicate a recurrence, which can be treated effectively upon early detection. But results from a new randomized, controlled trial presented at the annual meeting of the American Association of Clinical Oncology (ASCO) earlier this y...

Treatment of cancer with drugs: a controversy.

As radiation oncologists, we were greatly disappointed to read the recent editorial by the Spanish Society of Medical Oncology (SEOM) in this journal entitled ‘Treatment of Cancer with Oral Drugs: A Position Statement by the Spanish Society of Medical Oncology’ [1]. The editorial appears to be a call to grant medical oncologists the exclusive right to prescribe anticancer drugs and to give thes...